Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 55384
Gene Symbol: MEG3
MEG3
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		0.040 GeneticVariation BEFREE Increased methylation at CpG sites within the MEG3 promotor region was observed in AML patients having longer overall survival. 30876483

2019
Entrez Id: 55384
Gene Symbol: MEG3
MEG3
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		0.040 Biomarker BEFREE Taken together, our work demonstrates that TET2 dysregulated WT1-MEG3 axis significantly promotes AML leukemogenesis, paving a new avenue for diagnosis and treatment of AML patients. 28400619

2017
Entrez Id: 55384
Gene Symbol: MEG3
MEG3
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		0.040 AlteredExpression BEFREE Studies found that the MEG3 expression was significantly decreased in AML. 29029424

2017
Entrez Id: 55384
Gene Symbol: MEG3
MEG3
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		0.040 PosttranslationalModification BEFREE Moreover, there was greater methylation of MEG3 promoter in the AML patients than the controls (P < 0.05). 28407691

2017