Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
CUI: C0023480
Disease: Leukemia, Myelomonocytic, Chronic
Leukemia, Myelomonocytic, Chronic 		0.370 GeneticVariation BEFREE Overexpression of Arginase 1 is linked to DNMT3A and TET2 mutations in lower-grade myelodysplastic syndromes and chronic myelomonocytic leukemia. 29227812

2018
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
CUI: C0023480
Disease: Leukemia, Myelomonocytic, Chronic
Leukemia, Myelomonocytic, Chronic 		0.370 GeneticVariation BEFREE Gene sequencing detected a mutation in DNA methyltransferase 3α, which is relatively rarely identified in CMML and has recently been reported to have an independent prognostic impact on overall survival time. 29731877

2018
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
CUI: C0023480
Disease: Leukemia, Myelomonocytic, Chronic
Leukemia, Myelomonocytic, Chronic 		0.370 GeneticVariation BEFREE We carried out this study to assess the prognostic impact of DNMT3A mutations on a larger informative cohort of CMML patients (n = 261). 27733013

2017
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
CUI: C0023480
Disease: Leukemia, Myelomonocytic, Chronic
Leukemia, Myelomonocytic, Chronic 		0.370 GeneticVariation BEFREE First: This is the first report on CMML with double-mutations of DNMT3A and FLT3-ITD. 28102729

2017
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
CUI: C0023480
Disease: Leukemia, Myelomonocytic, Chronic
Leukemia, Myelomonocytic, Chronic 		0.370 GeneticVariation BEFREE We explored prognostic implications of gene mutations such as DNMT3A, issues related to the classification of AML cases with the NPM1 mutation, and myelodysplasia-related changes arising from chronic myelomonocytic leukemia after a short latency interval. 26071459

2015
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
CUI: C0023480
Disease: Leukemia, Myelomonocytic, Chronic
Leukemia, Myelomonocytic, Chronic 		0.370 GeneticVariation BEFREE DNMT3A Arg882 mutation drives chronic myelomonocytic leukemia through disturbing gene expression/DNA methylation in hematopoietic cells. 24497509

2014
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
CUI: C0023480
Disease: Leukemia, Myelomonocytic, Chronic
Leukemia, Myelomonocytic, Chronic 		0.370 Biomarker BEFREE Mutational spectrum analysis of chronic myelomonocytic leukemia includes genes associated with epigenetic regulation: UTX, EZH2, and DNMT3A. 21828135

2011