Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4297
Gene Symbol: KMT2A
KMT2A
CUI: C0023518
Disease: Leukocytosis
Leukocytosis 		0.030 GeneticVariation BEFREE Acute myeloid leukemias with MLL rearrangements are frequently associated with myelomonocytic and monoblastic/monocytic morphology, with an increased risk of leukocytosis and leukostasis-related complications. 25081372

2015
Entrez Id: 4297
Gene Symbol: KMT2A
KMT2A
CUI: C0023518
Disease: Leukocytosis
Leukocytosis 		0.030 Biomarker BEFREE Illustrating the technology, we show that MLL-ENL fusion is sufficient for lethal leukocytosis and proof of genome integrity comes from germline transmission of the sequentially targeted alleles. 24419086

2014
Entrez Id: 4297
Gene Symbol: KMT2A
KMT2A
CUI: C0023518
Disease: Leukocytosis
Leukocytosis 		0.030 GeneticVariation BEFREE Acute lymphoblastic leukemia (ALLs) expressing MLL-AF4, the fusion product of t(4;11)(q21;q23), show marked leucocytosis and extramedullary disease in multiple organs, respond poorly to chemotherapy and have poor prognosis. 14990976

2004