Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
CUI: C0025500
Disease: Mesothelioma
Mesothelioma 		0.380 Biomarker BEFREE We report that persistent C. trachomatis infection increases the expression of inflammatory tumour cytokines and upregulates molecular biomarkers such as podoplanin, Wilms' tumour gene 1 and osteopontin in primary cultures of mesothelial cells (Mes1) and human mesothelioma cells (NCI). 28535856

2017
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
CUI: C0025500
Disease: Mesothelioma
Mesothelioma 		0.380 Biomarker BEFREE Both SMRP and OPN in mesothelioma patients were significantly higher than in patients with other (non-mesothelioma) cancer and in healthy volunteers. 20131968

2010
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
CUI: C0025500
Disease: Mesothelioma
Mesothelioma 		0.380 Biomarker BEFREE Osteopontin-mediated enhanced hyaluronan binding induces multidrug resistance in mesothelioma cells. 20101228

2010
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
CUI: C0025500
Disease: Mesothelioma
Mesothelioma 		0.380 Biomarker BEFREE To determine the roles of OPN in MPM, immunohistochemical staining was performed to investigate the concentration of OPN in the pleural tumor of patients with mesothelioma; cell adhesion, proliferation and migration assays of H28 cells, an MPM cell line, were also carried out in vitro. 19528482

2009
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
CUI: C0025500
Disease: Mesothelioma
Mesothelioma 		0.380 Biomarker BEFREE Tumorigenic properties of alternative osteopontin isoforms in mesothelioma. 19285954

2009