Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1244
Gene Symbol: ABCC2
ABCC2
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.030 GeneticVariation BEFREE In conclusion, we found a promising association between ABCC2-rs4148388 and MM outcome that is supported by a plausible biological explanation. 30079960

2018
Entrez Id: 1244
Gene Symbol: ABCC2
ABCC2
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.030 Biomarker BEFREE Diffuse large B-cell lymphoma (DLBCL) and multiple myeloma (MM) cells infected by EBV display drug resistance-related proteins (MDR1, MRP1 and MRP2) and stem cell markers (OCT4 and SOX2). 28339079

2017
Entrez Id: 1244
Gene Symbol: ABCC2
ABCC2
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.030 GeneticVariation BEFREE We evaluated 21 germline SNPs of the gemcitabine metabolism genes CDA, deoxycytidine kinase, and hCNT3; DNA damage repair genes RECQL, X-ray repair complementing 1, RAD54L, ATM, ATR, MLH1, MSH2, MSH3, TREX1, EXO1, and TP73; and multidrug-resistance genes MRP2 and MRP5; as well as glutathione-S-transferase GSTP1 in 153 patients with relapsed or refractory lymphoma or myeloma receiving Gem/Bu/Mel. 26743341

2016