Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0026987
Disease: Myelofibrosis
Myelofibrosis 		0.040 Biomarker BEFREE Inhibition of NCT in myelofibrosis CD34<sup>+</sup> cells led to nuclear accumulation of p53. 30563936

2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0026987
Disease: Myelofibrosis
Myelofibrosis 		0.040 Biomarker BEFREE In myelodysplastic syndromes, significant myelofibrosis has been associated with adverse outcomes and p53 dysregulation. 29596070

2018
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0026987
Disease: Myelofibrosis
Myelofibrosis 		0.040 GeneticVariation BEFREE We found that blast phase of PV was characterized by overt myelodysplasia (n = 51, 88%); moderate to severe myelofibrosis (33 of 45, 73%); an abnormal karyotype (n = 51, 88%) that was often complex karyotype (n = 42, 72%); and gene mutations involving TP53 (55%), TET2 (27%), and DNMT3A (25%). 29285580

2018
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0026987
Disease: Myelofibrosis
Myelofibrosis 		0.040 Biomarker BEFREE Within the affected regions, we identified genes involved in bone marrow fibrosis (FGF12) and response to treatment (TP53) in individual cases. 18397341

2008