Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3205
Gene Symbol: HOXA9
HOXA9
CUI: C0027022
Disease: Myeloproliferative disease
Myeloproliferative disease 		0.060 Biomarker BEFREE However, mutant IDH1 greatly accelerated onset of myeloproliferative disease-like myeloid leukemia in mice in cooperation with HoxA9 with a mean latency of 83 days compared with cells expressing HoxA9 and wild-type IDH1 or a control vector (167 and 210 days, respectively, P = .001). 23954893

2013
Entrez Id: 3205
Gene Symbol: HOXA9
HOXA9
CUI: C0027022
Disease: Myeloproliferative disease
Myeloproliferative disease 		0.060 GeneticVariation BEFREE The human GFI136N variant induces epigenetic changes at the Hoxa9 locus and accelerates K-RAS driven myeloproliferative disorder in mice. 22932805

2012
Entrez Id: 3205
Gene Symbol: HOXA9
HOXA9
CUI: C0027022
Disease: Myeloproliferative disease
Myeloproliferative disease 		0.060 Biomarker BEFREE NUP98-HOXA9-transgenic zebrafish develop a myeloproliferative neoplasm and provide new insight into mechanisms of myeloid leukaemogenesis. 21810091

2011
Entrez Id: 3205
Gene Symbol: HOXA9
HOXA9
CUI: C0027022
Disease: Myeloproliferative disease
Myeloproliferative disease 		0.060 GeneticVariation BEFREE The NUP98-HOXA9 fusion gene with t(7;11)(p15;p15) was identified and revealed to be essential for leukemogenesis and myeloproliferative disease. 19338047

2009
Entrez Id: 3205
Gene Symbol: HOXA9
HOXA9
CUI: C0027022
Disease: Myeloproliferative disease
Myeloproliferative disease 		0.060 AlteredExpression BEFREE Expression of NUP98-HOXA9 in murine bone marrow resulted in a myeloproliferative disease progressing to AML by 7-8 months. 17442773

2007
Entrez Id: 3205
Gene Symbol: HOXA9
HOXA9
CUI: C0027022
Disease: Myeloproliferative disease
Myeloproliferative disease 		0.060 AlteredExpression BEFREE Mice transplanted with bone marrow cells expressing NUP98-HOXA9 through retroviral transduction acquire a myeloproliferative disease (MPD) and eventually succumb to acute myeloid leukemia (AML). 11157742

2001