Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0027022
Disease: Myeloproliferative disease
Myeloproliferative disease 		0.040 Biomarker BEFREE Defective negative regulation of Toll-like receptor signaling leads to excessive TNF-α in myeloproliferative neoplasm. 30647074

2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0027022
Disease: Myeloproliferative disease
Myeloproliferative disease 		0.040 GeneticVariation BEFREE Association of TNF polymorphisms with JAK2 (V617F) myeloproliferative neoplasms in Brazilian patients. 26852656

2016
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0027022
Disease: Myeloproliferative disease
Myeloproliferative disease 		0.040 Biomarker BEFREE TNFα facilitates clonal expansion of JAK2V617F positive cells in myeloproliferative neoplasms. 21860020

2011
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0027022
Disease: Myeloproliferative disease
Myeloproliferative disease 		0.040 AlteredExpression BEFREE In a murine retroviral bone marrow transduction-transplantation model, a Tel (exon 1-5)-Abl fusion protein induced 2 distinct illnesses: a CML-like myeloproliferative disease very similar to that induced by Bcr-Abl but with increased latency and a novel syndrome characterized by small-bowel myeloid cell infiltration and necrosis, increased circulating endotoxin and tumor necrosis factor alpha levels, and fulminant hepatic and renal failure. 12036890

2002