Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 100422896
Gene Symbol: MIR3140
MIR3140
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.020 Biomarker BEFREE Here, we show that miR-3140, which was identified as a novel tumor suppressive miRNA by function-based screening of a library containing 1090 miRNA mimics, directly suppressed BRD4 by binding to its coding sequence (CDS). miR-3140 concurrently downregulated BRD3 by bind to its CDS as well as CDK2 and EGFR by binding to their 3' untranslated regions. miR-3140 inhibited tumor cell growth in vitro in various cancer cell lines, including EGFR tyrosine kinase inhibitor-resistant cells. 29540837

2018
Entrez Id: 100422896
Gene Symbol: MIR3140
MIR3140
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.020 Biomarker BEFREE Publisher Correction: miR-3140 suppresses tumor cell growth by targeting BRD4 via its coding sequence and downregulates the BRD4-NUT fusion oncoprotein. 29691442

2018