Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 252983
Gene Symbol: STXBP4
STXBP4
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.030 Biomarker BEFREE Interestingly, STXBP4 is a potential tumor suppressor for human kidney cancer, whose downregulation is correlated with YAP activation in clear cell renal cell carcinoma. 31782549

2020
Entrez Id: 252983
Gene Symbol: STXBP4
STXBP4
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.030 AlteredExpression BEFREE In line with this, both the stable RL7-ΔNp63α variant and Stxbp4 have oncogenic activity in soft agar and xenograft tumor assays. 29735662

2018
Entrez Id: 252983
Gene Symbol: STXBP4
STXBP4
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.030 Biomarker BEFREE In line with this, shRNA mediated <i>STXBP4</i> and <i>PDGFRA</i> knockdown suppressed tumor growth in soft-agar and xenograft assays.<b>Conclusions:</b> STXBP4 plays a crucial role in driving SCC growth and is an independent prognostic factor for predicting worse outcome in lung SCC. 28087642

2017