Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 796
Gene Symbol: CALCA
CALCA
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
0.360 Biomarker BEFREE Calcitonin may possess the potential for treating osteoarthritis, but to date the hormone has not been studied in the treatment of FJD. 29748528

2018

Entrez Id: 796
Gene Symbol: CALCA
CALCA
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
0.360 Biomarker BEFREE This study was mainly aimed to explore the effects of CT on the treatment of OA, as well as the underlying mechanisms. 28514714

2017

Entrez Id: 796
Gene Symbol: CALCA
CALCA
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
0.360 Biomarker BEFREE Calcitonin gene-related peptide (CGRP) is a vasodilatory neuropeptide that is localized to joint tissues and has recently been implicated in the development of knee OA and OA pain. 28431586

2017

Entrez Id: 796
Gene Symbol: CALCA
CALCA
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
0.360 Biomarker BEFREE PGE2 appears to regulate CGRP/CGRP receptor signaling through the EP receptor in the synovium of knee OA patients. 27751171

2016

Entrez Id: 796
Gene Symbol: CALCA
CALCA
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
0.360 Biomarker BEFREE To investigate the regulation of CGRP/CGRP receptor signalling by macrophages in the synovial tissue (ST) of OA joints, we characterized the gene expression profiles of CGRP and CGRP receptors in the ST of OA mice (STR/Ort). 26400621

2016

Entrez Id: 796
Gene Symbol: CALCA
CALCA
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
0.360 Biomarker BEFREE Calcitonin (CT) has been suggested to have chondroprotective effects; therefore, could play a role in the pathogenesis of OA of the knee. 19736013

2010