Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 283131
Gene Symbol: NEAT1
NEAT1
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.070 Biomarker BEFREE In addition, our studies showed that miR-186-5p was a downstream target of NEAT1 in OS. 30485482

2019
Entrez Id: 283131
Gene Symbol: NEAT1
NEAT1
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.070 Biomarker BEFREE These results indicated that NEAT1 could function as a tumor oncogene in OS by inhibiting miR-339-5p in vitro. 30203547

2019
Entrez Id: 283131
Gene Symbol: NEAT1
NEAT1
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.070 AlteredExpression BEFREE Overexpression of NEAT1 markedly accelerated proliferative and reduced apoptosis potentials of osteosarcoma cells. 31044561

2019
Entrez Id: 283131
Gene Symbol: NEAT1
NEAT1
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.070 Biomarker BEFREE Furthermore, overexpressed NEAT1 reduced the sensitivity of cisplatin (DDP) and inhibited DDP-induced apoptosis and cell cycle arrest via <i>miR-34c</i> The results <i>in vivo</i> also confirmed that knockdown of NEAT1 sensitized the OS cells to DPP-induced tumor regression, delayed the tumor growth with reduced levels of Ki-67, BCL-2, and cyclin D1 signals, suggesting that NEAT1 is an oncogene and chemotherapy resistant factor in OS. 29654165

2018
Entrez Id: 283131
Gene Symbol: NEAT1
NEAT1
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.070 AlteredExpression BEFREE <b>Conclusion:</b> LncRNA NEAT1 was up-regulated in osteosarcoma tissue, promoting proliferation and metastasis of osteosarcoma cells. 30123061

2018
Entrez Id: 283131
Gene Symbol: NEAT1
NEAT1
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.070 AlteredExpression BEFREE Overexpression of NEAT1 in OS tissues was correlated with higher clinical stage, distant metastasis and poorer prognosis. 29416922

2018
Entrez Id: 283131
Gene Symbol: NEAT1
NEAT1
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.070 Biomarker BEFREE Furthermore, inhibition of miR-194 reversed the suppression of proliferation and invasion and the promotion of apoptosis induced by NEAT1 depletion in osteosarcoma cells. 29047232

2017