Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 29843
Gene Symbol: SENP1
SENP1
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.030 AlteredExpression BEFREE [Corrigendum] Overexpression of SENP1 reduces the stemness capacity of osteosarcoma stem cells and increases their sensitivity to HSVtk/GCV. 30896859

2019
Entrez Id: 29843
Gene Symbol: SENP1
SENP1
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.030 Biomarker BEFREE The purpose of the present study was to investigate the role and underlying mechanism of SUMO-specific protease 1 (SENP1)/hypoxia-inducible factor-1α (HIF-1α) feedback loop in hypoxic microenvironment of OS. 28796315

2018
Entrez Id: 29843
Gene Symbol: SENP1
SENP1
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.030 AlteredExpression BEFREE Finally, SENP1 overexpression led to a significant increase in the sensitivity of osteosarcoma stem cells to the herpes simplex virus 1 thymidine kinase gene in combination with ganciclovir in vitro and in vivo. 30226577

2018