Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3725
Gene Symbol: JUN
JUN
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.350 AlteredExpression BEFREE In our study, we demonstrate that activator protein 1 family members induce osteosarcomagenesis in immortalized hMSC. c-JUN or c-JUN/c-FOS overexpression act as tumorigenic factors generating OS with fibroblastic or pleomorphic osteoblastic phenotypes, respectively.Stem Cells 2018;36:1487-1500. 30001480

2018
Entrez Id: 3725
Gene Symbol: JUN
JUN
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.350 Biomarker BEFREE In addition, our analyses reveal a possible cooperation between aberrantly activated HIF-1α and AP-1 genetic pathways in OS metastasis. 27072870

2016
Entrez Id: 3725
Gene Symbol: JUN
JUN
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.350 Biomarker BEFREE The binding of transcription factor AP-1 and vitamin D receptor (VDR) to the composite AP-1 plus vitamin-D-responsive promoter region (AP-1 + VDRE) of the human osteocalcin gene was characterized in osteocalcin-producing (MG-63) and non-producing (U2-Os, SaOs-2) human osteosarcoma cell lines. 8076631

1994