Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 471
Gene Symbol: ATIC
ATIC
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.020 GeneticVariation BEFREE Even though the role of single nucleotide polymorphisms of ATIC in chemotherapy-induced tumor necrosis has not been investigated yet, the ATIC 347C>G polymorphism may influence the levels of adenosine after MTX treatment, which may affect the histologic response of osteosarcoma. 28267080

2017
Entrez Id: 471
Gene Symbol: ATIC
ATIC
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.020 Biomarker BEFREE AMPK inhibition by compound C or RNA interference suppressed capsaicin-induced cytotoxicity, while AMPK activators (AICAR and A769662) promoted osteosarcoma cell death. 24005536

2013