Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma 		0.050 Biomarker BEFREE The contribution of the endothelin-1 (ET-1)/ET A receptor (ETAR) axis in tumor growth and progression is investigated in many tumor types, including ovarian carcinoma. 20725137

2010
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma 		0.050 Biomarker BEFREE Endothelin-1 (ET-1) has been implicated in the progression of various cancers, including ovarian carcinoma. 19010899

2008
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma 		0.050 Biomarker BEFREE Integrin-linked kinase functions as a downstream mediator of endothelin-1 to promote invasive behavior in ovarian carcinoma. 16648553

2006
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma 		0.050 Biomarker BEFREE Collectively, these findings provide evidence of a critical role for the ET-1/ET(A)R axis during distinct steps of ovarian carcinoma progression and identify novel targets of therapeutic intervention. 16357176

2005
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma 		0.050 Biomarker BEFREE The present study was designed to investigate the effects of the ET(A)-selective antagonist ABT-627 on the ET-1-induced mitogenic effect in both primary cultures (PMOV1 and PMOV2) and cell lines (OVCA 433 and HEY) of ovarian carcinoma. 12193113

2002