Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.600 Biomarker BEFREE Prostate tumours with β-catenin activation relied on the non-canonical WNT ligand WNT5a for sustained growth. 31719098

2020
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.600 AlteredExpression BEFREE MMP7 disrupted E-cadherin/β-catenin complex to upregulate EMT transcription factors in mouse prostate tumors. 27375020

2017
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.600 AlteredExpression BEFREE We found that expression of the ALDH1A1 gene is regulated by the WNT signaling pathway and co-occurs with expression of β-catenin in prostate tumor specimens. 25670168

2015
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.600 GeneticVariation BEFREE Although beta-catenin stability is regulated by a multicomponent destruction complex, mutational alterations of beta-catenin or other components of the destruction complexes are rare in prostate tumors. 18819930

2008
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.600 GeneticVariation BEFREE It was previously shown that 5% of prostate tumors harbor CTNNB1 mutations, suggesting that this tumor type may involve a deregulated APC/CTNNB1 pathway. 11921277

2002