Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2324
Gene Symbol: FLT4
FLT4
CUI: C0038436
Disease: Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder
0.100 Biomarker BEFREE Fifty-six patients (71% female, 61% White) with mixed etiology chronic pain completed the PTSD Checklist-Civilian Version (PCL-C) as part of their appointment with a pain psychologist at a tertiary outpatient pain clinic. 31646748

2020

Entrez Id: 2324
Gene Symbol: FLT4
FLT4
CUI: C0038436
Disease: Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder
0.100 GeneticVariation BEFREE PTSD and partial PTSD were measured using the PCL-5. 31821960

2020

Entrez Id: 2324
Gene Symbol: FLT4
FLT4
CUI: C0038436
Disease: Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder
0.100 GeneticVariation BEFREE PTSD Checklist-Civilian Version (PCL-C); Neurobehavioral Symptom Inventory (NSI); Ohio State University TBI Identification Method; Patient Health Questionnaire-9 (PHQ-9); Simoa-measured concentrations of tau, amyloid-beta (Aβ) 40, Aβ42, and neurofilament light (NFL). 31033745

2020

Entrez Id: 2324
Gene Symbol: FLT4
FLT4
CUI: C0038436
Disease: Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder
0.100 Biomarker BEFREE PTSD symptoms were measured by the PTSD Checklist for DSM-5 (PCL-5), and the severity (total symptoms) and symptom clusters were calculated according to the hybrid seven-factor model of DSM-5 PTSD. 31655035

2020

Entrez Id: 2324
Gene Symbol: FLT4
FLT4
CUI: C0038436
Disease: Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder
0.100 GeneticVariation BEFREE Altogether, 333 survivors were surveyed (130 in July 2015 and 203 in March 2016) with PCL-5 as the screening instrument, using the cutoff score of 38 or more for diagnosing PTSD. 29085091

2019

Entrez Id: 2324
Gene Symbol: FLT4
FLT4
CUI: C0038436
Disease: Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder
0.100 GeneticVariation BEFREE For example, 2.8% of PTSD-negative participants versus 15.9% of PTSD-positive participants recalled experiencing 20+ more points on the PCL-5 at follow-up than at initial assessment. 30849715

2019

Entrez Id: 2324
Gene Symbol: FLT4
FLT4
CUI: C0038436
Disease: Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder
0.100 Biomarker BEFREE PTSD was assessed by the PTSD Checklist Civilian Version (PCL-C). 30470649

2019

Entrez Id: 2324
Gene Symbol: FLT4
FLT4
CUI: C0038436
Disease: Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder
0.100 GeneticVariation BEFREE <b>Methods</b>: Thirty-three patients newly admitted to an inpatient unit for treatment of trauma-related disorders received a standardized self-assessment package, including the PTSD Checklist for DSM-5 (PCL-5), the Moral Injury Events Scale (MIES; adapted for the Canadian context), and the Adverse Childhood Experiences Questionnaire (ACE-Q), which is a retrospective measure of childhood abuse. 30693070

2019

Entrez Id: 2324
Gene Symbol: FLT4
FLT4
CUI: C0038436
Disease: Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder
0.100 GeneticVariation BEFREE Participants (<i>N</i> = 380) were veterans who completed the PTSD Checklist for <i>DSM-5</i> (PCL-5; Weathers et al., 2013) and the Clinician-Administered PTSD Scale for <i>DSM-5</i> (CAPS-5; Weathers et al., 2013).Fit was similar across models. 30113182

2019

Entrez Id: 2324
Gene Symbol: FLT4
FLT4
CUI: C0038436
Disease: Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder
0.100 Biomarker BEFREE PTSD symptom severity and depressive symptoms were assessed using the PTSD specific-trauma checklist (PCL-S) and the Patient Health Questionnaire (PHQ-9). 30934818

2019

Entrez Id: 2324
Gene Symbol: FLT4
FLT4
CUI: C0038436
Disease: Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder
0.100 Biomarker BEFREE The PTSD Checklist Civilian Version (PCL-C) was used to assess PTSD. 30269201

2019

Entrez Id: 2324
Gene Symbol: FLT4
FLT4
CUI: C0038436
Disease: Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder
0.100 Biomarker BEFREE The PCL-C (PTSD), the PHQ-8 (MDD), and PG-13 (PGD) were used to measure mental health disorders. 31543835

2019

Entrez Id: 2324
Gene Symbol: FLT4
FLT4
CUI: C0038436
Disease: Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder
0.100 GeneticVariation BEFREE However, a significant interaction effect between GHRL rs696217 and HCRTR1 rs2271933 was found to predict the PTSD Checklist (PCL-5) total score (P =  0.007). 30326460

2019

Entrez Id: 2324
Gene Symbol: FLT4
FLT4
CUI: C0038436
Disease: Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder
0.100 GeneticVariation BEFREE Sixty-seven patients with PTSD and 72 patients without PTSD were assessed using the PTSD Checklist for DSM-5 (PCL-5) and psychiatric interview. 30579176

2019

Entrez Id: 2324
Gene Symbol: FLT4
FLT4
CUI: C0038436
Disease: Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder
0.100 GeneticVariation BEFREE Study patients were screened for PTSD using the PCL-5 checklist for DSM-5. 30878218

2019

Entrez Id: 2324
Gene Symbol: FLT4
FLT4
CUI: C0038436
Disease: Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder
0.100 Biomarker BEFREE The subjects were evaluated using the sociodemographic questionnaire, PTSD self-report checklist (PCL-5) and Short Form (SF-36) Health Survey questionnaire. 31291223

2019

Entrez Id: 2324
Gene Symbol: FLT4
FLT4
CUI: C0038436
Disease: Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder
0.100 Biomarker BEFREE Our goal is to demonstrate a practical and actionable process for factor analysis through (a) an overview of six statistical and psychometric issues and approaches to be aware of, investigate, and report when engaging in factor structure validation, along with a flowchart for recommended procedures to understand latent factor structures; (b) demonstrating these issues to provide a summary of the updated Posttraumatic Stress Disorder Checklist (PCL-5) factor models and a rationale for validation; and (c) conducting a comprehensive statistical and psychometric validation of the PCL-5 factor structure to demonstrate all the issues we described earlier. 29630411

2019

Entrez Id: 2324
Gene Symbol: FLT4
FLT4
CUI: C0038436
Disease: Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder
0.100 Biomarker BEFREE The PTSD Check list-Civilian Version (PCL-C) was used at all time points. 30551022

2019

Entrez Id: 2324
Gene Symbol: FLT4
FLT4
CUI: C0038436
Disease: Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder
0.100 GeneticVariation BEFREE A total of 16 subjects were analyzed; of those, seven (43.8%) screened positive for PTSD with the PCL-C. 31508823

2019

Entrez Id: 2324
Gene Symbol: FLT4
FLT4
CUI: C0038436
Disease: Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder
0.100 GeneticVariation BEFREE At 3 months, PTSD will be defined by a ≥ 33 score at PTSD Check List for DSM-5 (PCL-5) through a telephone interview. 31146712

2019

Entrez Id: 2324
Gene Symbol: FLT4
FLT4
CUI: C0038436
Disease: Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder
0.100 GeneticVariation BEFREE The second study established criterion validity of the PCL-5 using the PTSD module of the Mini-International Neuropsychiatric Interview (MINI), delivered by a female Filipino psychologist as the criterion, in a sample of 100 participants. 30774783

2019

Entrez Id: 2324
Gene Symbol: FLT4
FLT4
CUI: C0038436
Disease: Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder
0.100 Biomarker BEFREE Method A link to an online questionnaire containing 27 questions, including residency training and year, as well as the PTSD Checklist for Diagnostic and Statistical Manual of Mental Disorders-fifth edition (PCL-5) was e-mailed and completed by the resident physicians of the University of British Columbia. 31404354

2019

Entrez Id: 2324
Gene Symbol: FLT4
FLT4
CUI: C0038436
Disease: Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder
0.100 Biomarker BEFREE Retrospective and current measures of PTSD (PTSD Checklist for DSM-5 [PCL-5]) and suicidality (Suicidal Ideation Attributes Scale [SIDAS-5]) were used. 30375881

2019

Entrez Id: 2324
Gene Symbol: FLT4
FLT4
CUI: C0038436
Disease: Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder
0.100 GeneticVariation BEFREE <b>Method</b>: Three groups of asylum seekers from different countries (<i>N</i> = 99) completed the Traumatic Grief Inventory Self-Report Version (TGI-SR), Posttraumatic Stress Disorder Checklist-5 (PCL-5), and Patient Health Questionnaire depression module (PHQ-9). 30988893

2019

Entrez Id: 2324
Gene Symbol: FLT4
FLT4
CUI: C0038436
Disease: Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder
0.100 Biomarker BEFREE PTSD symptom severity was measured using the PTSD Checklist for <i>Diagnostic and Statistical Manual of Mental Disorders-Fifth Edition</i> (PCL-5). 31679445

2019