Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 56848
Gene Symbol: SPHK2
SPHK2
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction 		0.010 Biomarker BEFREE Functionally, Sphk2-deficient (Sphk2<sup>-/-</sup>) mice showed an attenuated fibrotic response to UUO compared with wild-type mice, as demonstrated by reduced collagen abundance and decreased expression of fibronectin-1, collagen I, α-smooth muscle actin, connective tissue growth factor (CTGF), and plasminogen activator inhibitor (PAI-1). 28807595

2017