| Gene | Disease | Score gda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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0.060 | GeneticVariation | BEFREE | Identification of novel therapeutic targets in acute leukemias with NRAS mutations using a pharmacologic approach. | 25833960 | 2015 |
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0.060 | GeneticVariation | BEFREE | Analysis of KRAS and NRAS Gene Mutations in Arab Asian Children With Acute Leukemia: High Frequency of RAS Mutations in Acute Lymphoblastic Leukemia. | 26222068 | 2015 |
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0.060 | GeneticVariation | BEFREE | K-Ras mutations and N-Ras mutations in childhood acute leukemias with or without mixed-lineage leukemia gene rearrangements. | 16404744 | 2006 |
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0.060 | GeneticVariation | BEFREE | The authors analyzed MIN in de novo acute leukemia and its association with expression of the human MSH3 (hMSH3) gene and point mutations of the N-ras gene. | 9690540 | 1998 |
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0.060 | Biomarker | BEFREE | A trend was found between the overexpression of the N-ras gene and the acute leukemias: all 10 acute leukemias exhibited overexpression of the N-ras gene, while only two of the CML cases, both in blastic crisis, showed elevated levels of the N-ras gene. | 8948029 | 1996 |
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0.060 | AlteredExpression | BEFREE | Our observations indicate that in vivo selection assays detect transforming genes including ras oncogenes at high frequency, and that activated N-ras genes are frequently detected in human acute leukemias. | 3632661 | 1987 |