Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 208
Gene Symbol: AKT2
AKT2
CUI: C0178874
Disease: Tumor Progression
Tumor Progression 		0.060 Biomarker BEFREE Taking account of conflicting findings among the studies, the majority of the studies reported a tumor initiating role of AKT1, whereas AKT2 is mainly responsible for tumor progression and metastasis. 31752925

2019
Entrez Id: 208
Gene Symbol: AKT2
AKT2
CUI: C0178874
Disease: Tumor Progression
Tumor Progression 		0.060 Biomarker BEFREE In an in-depth literature review, we focus on the role of AKT2 activation and its consequences on the tumor progression in different cancers. 29199386

2018
Entrez Id: 208
Gene Symbol: AKT2
AKT2
CUI: C0178874
Disease: Tumor Progression
Tumor Progression 		0.060 Biomarker BEFREE AKT (also known as protein kinase B, PKB) plays an important role in cell survival or tumor progression. 29299162

2017
Entrez Id: 208
Gene Symbol: AKT2
AKT2
CUI: C0178874
Disease: Tumor Progression
Tumor Progression 		0.060 Biomarker BEFREE Akt2 is strongly associated with cancer progression, cellular migration, and promotion of epithelial-mesenchymal transition. 20197381

2010
Entrez Id: 208
Gene Symbol: AKT2
AKT2
CUI: C0178874
Disease: Tumor Progression
Tumor Progression 		0.060 Biomarker BEFREE Akt/PKB is a crucial regulator of diverse cellular processes and contributes to cancer progression. 14761976

2004
Entrez Id: 208
Gene Symbol: AKT2
AKT2
CUI: C0178874
Disease: Tumor Progression
Tumor Progression 		0.060 Biomarker BEFREE Although the mechanisms have not yet been fully characterised, constitutive PKB/Akt signalling is believed to promote proliferation and increased cell survival and thereby contributing to cancer progression. 11882383

2002