Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4921
Gene Symbol: DDR2
DDR2
CUI: C0178874
Disease: Tumor Progression
Tumor Progression 		0.060 Biomarker BEFREE Given that DDR2 has a crucial role in the epithelial-to-mesenchymal transition and cancer progression, targeting the HSP47-DDR2 interaction might be a potential strategy for inhibiting DDR2-dependent cancer progression. 31570520

2019
Entrez Id: 4921
Gene Symbol: DDR2
DDR2
CUI: C0178874
Disease: Tumor Progression
Tumor Progression 		0.060 AlteredExpression BEFREE Overexpression of DDR2 might contribute to tumor progression in lung SQCC. 28676216

2017
Entrez Id: 4921
Gene Symbol: DDR2
DDR2
CUI: C0178874
Disease: Tumor Progression
Tumor Progression 		0.060 AlteredExpression BEFREE The expression of the mutant DDR2 induced activation of DDR2 by the collagen ligand and caused enhanced cell growth and tumor progression. 28161936

2017
Entrez Id: 4921
Gene Symbol: DDR2
DDR2
CUI: C0178874
Disease: Tumor Progression
Tumor Progression 		0.060 GeneticVariation BEFREE The DDR2 E655K mutation can play a role in cancer progression by reducing the growth-inhibitory effect of collagen. 26826182

2016
Entrez Id: 4921
Gene Symbol: DDR2
DDR2
CUI: C0178874
Disease: Tumor Progression
Tumor Progression 		0.060 Biomarker BEFREE Previous studies have suggested that discoidin domain receptor 2 (DDR2) is related to tumor progression and EMT. 27010547

2016
Entrez Id: 4921
Gene Symbol: DDR2
DDR2
CUI: C0178874
Disease: Tumor Progression
Tumor Progression 		0.060 Biomarker BEFREE Hence, our current data disclose a new mechanism by which DDR2 affects tumour progression, and may strengthen the feasibility of targeting DDR2 as an anticancer strategy. 24293323

2014