Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4513
Gene Symbol: COX2
COX2
CUI: C0220641
Disease: Lip and Oral Cavity Carcinoma
Lip and Oral Cavity Carcinoma 		0.090 Biomarker BEFREE Correlation of Inflammatory Markers, Survival, and COX2 Expression in Oral Cancer and Implications for Prognosis. 29359615

2018
Entrez Id: 4513
Gene Symbol: COX2
COX2
CUI: C0220641
Disease: Lip and Oral Cavity Carcinoma
Lip and Oral Cavity Carcinoma 		0.090 GeneticVariation BEFREE Several electronic databases were searched for published studies using combinations of keywords related to COX-2 gene polymorphisms and oral cancer. 25977924

2015
Entrez Id: 4513
Gene Symbol: COX2
COX2
CUI: C0220641
Disease: Lip and Oral Cavity Carcinoma
Lip and Oral Cavity Carcinoma 		0.090 Biomarker BEFREE PGE2 production in oral cancer cell lines is COX-2-dependent. 19278989

2009
Entrez Id: 4513
Gene Symbol: COX2
COX2
CUI: C0220641
Disease: Lip and Oral Cavity Carcinoma
Lip and Oral Cavity Carcinoma 		0.090 AlteredExpression BEFREE COX-2 expression in oral cancer was found to be independent of grade of tumor and stage of disease. 18356024

2008
Entrez Id: 4513
Gene Symbol: COX2
COX2
CUI: C0220641
Disease: Lip and Oral Cavity Carcinoma
Lip and Oral Cavity Carcinoma 		0.090 AlteredExpression BEFREE In conclusion, this study demonstrates correlation between over expression of NF-kappaB and COX-2 in early precancerous stages of development of oral cancer and sustained elevation down the tumorigenic pathway, underscoring their potential as targets for early intervention. 17354234

2007
Entrez Id: 4513
Gene Symbol: COX2
COX2
CUI: C0220641
Disease: Lip and Oral Cavity Carcinoma
Lip and Oral Cavity Carcinoma 		0.090 AlteredExpression BEFREE We measured COX-1 and COX-2 m-RNA expression in samples of both oral cancer and matched oral mucosa from 22 patients by RealTime RT-PCR; clinic pathological data (grading, TNM staging, inflammation, follow-up) of all patients were available for statistical evaluation. 17624243

2007
Entrez Id: 4513
Gene Symbol: COX2
COX2
CUI: C0220641
Disease: Lip and Oral Cavity Carcinoma
Lip and Oral Cavity Carcinoma 		0.090 AlteredExpression BEFREE Butyrate inhibits oral cancer cell proliferation and regulates expression of secretory phospholipase A2-X and COX-2. 17595767

2007
Entrez Id: 4513
Gene Symbol: COX2
COX2
CUI: C0220641
Disease: Lip and Oral Cavity Carcinoma
Lip and Oral Cavity Carcinoma 		0.090 Biomarker BEFREE Molecular targeting of COX-2, PGE(2) synthase, or PGE(2) receptors may be useful as a chemopreventive or therapeutic strategy for oral cancer. 12738747

2003
Entrez Id: 4513
Gene Symbol: COX2
COX2
CUI: C0220641
Disease: Lip and Oral Cavity Carcinoma
Lip and Oral Cavity Carcinoma 		0.090 AlteredExpression BEFREE COX-2 expression was correlated to DNA content as a genetic risk marker of oral cancer. 12747975

2003