Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3
CUI: C0235782
Disease: Gallbladder Carcinoma
Gallbladder Carcinoma 		0.130 AlteredExpression BEFREE Ectopic expression of ERBB2/ERBB3 mutants upregulated PD-L1 expression in GBC cells, effectively suppressed normal T-cell-mediated cytotoxicity in vitro through activation of the PI3K/Akt signalling pathway and contributed to the growth and progression of GBC in vivo. 29954840

2019
Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3
CUI: C0235782
Disease: Gallbladder Carcinoma
Gallbladder Carcinoma 		0.130 Biomarker BEFREE HER3 overexpression was predominantly cytoplasmic; the rate of overexpression/amplification of HER3 in membrane and cytoplasm was 16% [ampullary cancer (AMP) (1/13; 8%), gallbladder cancer (GBC) (1/10; 10%), intra-hepatic cholangiocarcinoma (ICC) (6/26; 23%), extra-hepatic cholangiocarcinoma (ECC) (3/18; 17%)] and 24% [AMP (1/13; 8%), GBC (1/10; 10%), ICC (10/26; 38%), ECC (4/18; 22%)], respectively. 30335866

2018
Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3
CUI: C0235782
Disease: Gallbladder Carcinoma
Gallbladder Carcinoma 		0.130 Biomarker BEFREE In addition, protein expression analysis by western blot for ERK1/2, p-ERK1/2, EGFR, ERBB2 and ERBB3 were performed in seven GBC cell lines (GB-d1, G415, NOZ, OCUG-1, TGBC-1, TGBC-2 and TGBC-24). 28285962

2017