×
Entrez Id:
5294
Gene Symbol:
PIK3CG
PIK3CG
Gallbladder Carcinoma
0.100
Biomarker
BEFREE
CCL18 secreted from M2 macrophages promotes migration and invasion via the PI3K /Akt pathway in gallbladder cancer .
30276551
2019
×
Entrez Id:
5294
Gene Symbol:
PIK3CG
PIK3CG
Gallbladder Carcinoma
0.100
Biomarker
BEFREE
DMBT1 suppresses progression of gallbladder carcinoma through PI3K /AKT signaling pathway by targeting PTEN.
31411121
2019
×
Entrez Id:
5294
Gene Symbol:
PIK3CG
PIK3CG
Gallbladder Carcinoma
0.100
AlteredExpression
BEFREE
Ectopic expression of ERBB2/ERBB3 mutants upregulated PD-L1 expression in GBC cells, effectively suppressed normal T-cell-mediated cytotoxicity in vitro through activation of the PI3K /Akt signalling pathway and contributed to the growth and progression of GBC in vivo.
29954840
2019
×
Entrez Id:
5294
Gene Symbol:
PIK3CG
PIK3CG
Gallbladder Carcinoma
0.100
Biomarker
BEFREE
Consistent with STYK1 gene knockdown, AKT specific inhibitor MK2206 abrogated tumor promoting action induced by STYK1, suggesting that PI3K /AKT pathway is essential for the oncogenic role of STYK1 in GBC .
29413947
2018
×
Entrez Id:
5294
Gene Symbol:
PIK3CG
PIK3CG
Gallbladder Carcinoma
0.100
Biomarker
BEFREE
In conclusion, miR-143-3p suppresses tumour angiogenesis and growth of GBC through the ITGA6/PI3K /AKT/PLGF pathways and may be a novel molecular therapeutic target for GBC .
29416013
2018
×
Entrez Id:
5294
Gene Symbol:
PIK3CG
PIK3CG
Gallbladder Carcinoma
0.100
AlteredExpression
BEFREE
The depletion of BRD4 in GBC cell lines resulted in obvious cell apoptosis and downregulated the expression levels of Bcl-2, p-PI3K and p-AKT.
28766687
2017
×
Entrez Id:
5294
Gene Symbol:
PIK3CG
PIK3CG
Gallbladder Carcinoma
0.100
Biomarker
BEFREE
Taken together, these findings indicate that DSN induces GBC apoptosis through inhibiting ROS-mediated PI3K /AKT signalling.
28656003
2017
×
Entrez Id:
5294
Gene Symbol:
PIK3CG
PIK3CG
Gallbladder Carcinoma
0.100
GeneticVariation
BEFREE
PIK3CA, which encodes the phosphoinositide 3-kinase (PI3K ) subunit p110α, is frequently mutated in many cancers, including GBC .
27317099
2016
×
Entrez Id:
5294
Gene Symbol:
PIK3CG
PIK3CG
Gallbladder Carcinoma
0.100
GeneticVariation
BEFREE
Mutations in exons 9 (E542K , E545G , E545K ) and 20 (H1047L and H1047R ) of PI3K were determined by direct sequencing in 130 cases of GBC .
26947513
2016
×
Entrez Id:
5294
Gene Symbol:
PIK3CG
PIK3CG
Gallbladder Carcinoma
0.100
AlteredExpression
BEFREE
We found that activation of the PI3K /Akt pathway was involved in the oncogenic functions of SPOCK1 in GBC .
25623055
2015