Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3952
Gene Symbol: LEP
LEP
CUI: C0236663
Disease: Alcohol withdrawal syndrome
Alcohol withdrawal syndrome 		0.330 PosttranslationalModification BEFREE The objective of our study was to investigate the dynamics of leptin gene promoter methylation during alcohol withdrawal and specific treatment in a rodent (rat) model for alcohol dependence. 30650427

2019
Entrez Id: 3952
Gene Symbol: LEP
LEP
CUI: C0236663
Disease: Alcohol withdrawal syndrome
Alcohol withdrawal syndrome 		0.330 PosttranslationalModification BEFREE DNA methylation of the LEP gene is associated with craving during alcohol withdrawal. 25462909

2015
Entrez Id: 3952
Gene Symbol: LEP
LEP
CUI: C0236663
Disease: Alcohol withdrawal syndrome
Alcohol withdrawal syndrome 		0.330 Biomarker BEFREE Our results show on the one hand negative associations between the number of CAG repeats and (i) leptin serum levels (P<0.01) and (ii) craving (P<0.05), and on the other hand, a positive association between leptin and craving of man in alcohol withdrawal (P<0.001). 19884906

2010