Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 65211
Gene Symbol: FRTS1
FRTS1
CUI: C0242596
Disease: Neoplasm, Residual
Neoplasm, Residual 		0.030 GeneticVariation BEFREE Gene mutations and pretransplant MRD predict high risk of relapse and worse RFS in patients with T-ALL after HSCT. 30950667

2019
Entrez Id: 65211
Gene Symbol: FRTS1
FRTS1
CUI: C0242596
Disease: Neoplasm, Residual
Neoplasm, Residual 		0.030 GeneticVariation BEFREE In patients with adverse cytogenetics, FLT3-ITD or MRD positivity, allogeneic hematopoietic stem cell transplantation (allo-HSCT) achieved superior 3-year CIR (0% vs. 52.8%; <i>p</i> = .006) and RFS (88.9% vs. 47.2%; <i>p</i> = .027) than did consolidation chemotherapy. 30773106

2019
Entrez Id: 65211
Gene Symbol: FRTS1
FRTS1
CUI: C0242596
Disease: Neoplasm, Residual
Neoplasm, Residual 		0.030 Biomarker BEFREE In comparison with the first cohort, the second cohort with the MRD assay incorporated prospectively, the standard risk (SR) and the intermediate risk (IR) patients showed a better RFS, EFS, and OS while the high-risk (HR) patients displayed worse RFS, EFS, and OS than those of the first cohort, respectively. 27212157

2016