Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 673
Gene Symbol: BRAF
BRAF
CUI: C0242596
Disease: Neoplasm, Residual
Neoplasm, Residual
0.020 Biomarker BEFREE Several different non-chemotherapy approaches are being used to target relapsed and refractory HCL, including inhibitors of BRAF, but so far only monoclonal antibody (MAb)-based approaches have been reported to eliminate MRD in a high percentage of patients. 26614902

2015

Entrez Id: 673
Gene Symbol: BRAF
BRAF
CUI: C0242596
Disease: Neoplasm, Residual
Neoplasm, Residual
0.020 GeneticVariation BEFREE The thymidine kinase inhibitor vemurafenib, which inhibits the V600E mutant of BRAF, was reported to induce a CR in multiply relapsed and refractory HCL, with nearly complete clearing of MRD. 23892906

2013