Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0242596
Disease: Neoplasm, Residual
Neoplasm, Residual 		0.040 GeneticVariation BEFREE In the 20 patients with high-risk features (17p or 11q deletions or TP53 mutation) and evaluable for efficacy, the ORR was 95%, with three patients (15%) achieving negative minimal residual disease.Median time to response was 8 weeks. 27982425

2017
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0242596
Disease: Neoplasm, Residual
Neoplasm, Residual 		0.040 Biomarker BEFREE Peripheral blood samples were analyzed for MRD at up to ten follow-up points while samples of MRD+ patients and patients who achieved partial clinical response after therapy were further analyzed for the presence of t(14;18) and P53 and RAS genes mutations. 18365550

2007
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0242596
Disease: Neoplasm, Residual
Neoplasm, Residual 		0.040 GeneticVariation BEFREE Limitations of the use of single base changes in the p53 gene to detect minimal residual disease of breast cancer. 12032228

2002
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0242596
Disease: Neoplasm, Residual
Neoplasm, Residual 		0.040 Biomarker BEFREE The p53 mutational diagnosis of metastatic cancer may be useful in detecting minimal residual disease. 10071815

1998