Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
CUI: C0271183
Disease: Severe myopia
Severe myopia 		0.090 GeneticVariation BEFREE Genetic variants in the IGF1 and IGF1R genes might not be associated with high myopia in Han Chinese. 27044882

2017
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
CUI: C0271183
Disease: Severe myopia
Severe myopia 		0.090 GeneticVariation BEFREE This meta-analysis showed there was no association detected between IGF1 rs6214 and high myopia. 28135889

2017
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
CUI: C0271183
Disease: Severe myopia
Severe myopia 		0.090 GeneticVariation BEFREE In addition, our results showed a nonsignificant association of the IGF-1 (rs6214-rs5742632) haplotype with either simple myopia or high-grade myopia. 27167306

2016
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
CUI: C0271183
Disease: Severe myopia
Severe myopia 		0.090 GeneticVariation BEFREE This meta-analysis shows that IGF-1 rs12423791 or rs6214 gene polymorphism is not associated with high myopia. 26076017

2015
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
CUI: C0271183
Disease: Severe myopia
Severe myopia 		0.090 Biomarker BEFREE Insulin-like growth factor 1 is not associated with high myopia in a large Japanese cohort. 23734076

2013
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
CUI: C0271183
Disease: Severe myopia
Severe myopia 		0.090 GeneticVariation BEFREE Association of insulin-like growth factor-1 polymorphisms with high myopia in the Chinese population. 22509095

2012
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
CUI: C0271183
Disease: Severe myopia
Severe myopia 		0.090 Biomarker BEFREE IGF1 is associated with high myopia, and identifying the causal variants is important for understanding the underlying mechanisms. 22332214

2012
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
CUI: C0271183
Disease: Severe myopia
Severe myopia 		0.090 GeneticVariation BEFREE Our results do not support recent studies reporting an association of the SNPs rs6214, rs10860860, and rs2946834 in the IGF-1 gene with HM and any myopia phenotypes. 21976954

2011
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
CUI: C0271183
Disease: Severe myopia
Severe myopia 		0.090 Biomarker BEFREE The study supports a genetic association between IGF-1 and high-grade myopia. 20435602

2010