×
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
Childhood Hepatocellular Carcinoma
0.330
Biomarker
BEFREE
Thyroid Hormone Receptor-β Agonist GC-1 Inhibits Met-β-Catenin -Driven Hepatocellular Cancer .
28807594 2017
×
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
Childhood Hepatocellular Carcinoma
0.330
Biomarker
BEFREE
Tumor suppressor function of ezrin-radixin-moesin-binding phosphoprotein-50 through β-catenin /E-cadherin pathway in human hepatocellular cancer .
23483729 2013
×
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
Childhood Hepatocellular Carcinoma
0.330
Biomarker
BEFREE
γ-Catenin at adherens junctions: mechanism and biologic implications in hepatocellular cancer after β-catenin knockdown.
23555187 2013
×
Entrez Id: 174
Gene Symbol: AFP
AFP
Childhood Hepatocellular Carcinoma
0.070
Biomarker
BEFREE
Hepatocellular cancer -derived alpha fetoprotein uptake reduces CD1 molecules on monocyte-derived dendritic cells.30392891 2019
×
Entrez Id: 174
Gene Symbol: AFP
AFP
Childhood Hepatocellular Carcinoma
0.070
GeneticVariation
BEFREE
By applying the approach to 286 hepatocellular tumour samples, they successfully uncover numerous driver aberration regions across the cancer genome, for example, chromosomes 4p and 5q, which harbour many known hepatocellular cancer related genes such as alpha-fetoprotein (AFP ) and ectodermal-neural cortex (ENC1).
25014222 2014
×
Entrez Id: 174
Gene Symbol: AFP
AFP
Childhood Hepatocellular Carcinoma
0.070
Biomarker
BEFREE
Alpha fetoprotein DNA prime and adenovirus boost immunization of two hepatocellular cancer patients.24708667 2014
×
Entrez Id: 174
Gene Symbol: AFP
AFP
Childhood Hepatocellular Carcinoma
0.070
Biomarker
BEFREE
AFP , PIVKAII, GP3, SCCA-1 and follisatin as surveillance biomarkers for hepatocellular cancer in non-alcoholic and alcoholic fatty liver disease.18638391 2008
×
Entrez Id: 174
Gene Symbol: AFP
AFP
Childhood Hepatocellular Carcinoma
0.070
AlteredExpression
BEFREE
Silencing alpha-fetoprotein expression induces growth arrest and apoptosis in human hepatocellular cancer cell.
18657899 2008
×
Entrez Id: 174
Gene Symbol: AFP
AFP
Childhood Hepatocellular Carcinoma
0.070
Biomarker
BEFREE
Hierarchy of alpha fetoprotein (AFP )-specific T cell responses in subjects with AFP -positive hepatocellular cancer .
16785570 2006
×
Entrez Id: 174
Gene Symbol: AFP
AFP
Childhood Hepatocellular Carcinoma
0.070
Biomarker
BEFREE
T-cell responses to HLA-A*0201 immunodominant peptides derived from alpha-fetoprotein in patients with hepatocellular cancer .
14676113 2003
×
Entrez Id: 6528
Gene Symbol: SLC5A5
SLC5A5
Childhood Hepatocellular Carcinoma
0.040
Biomarker
BEFREE
The dual-targeting approach was used to deliver the theranostic sodium iodide symporter (NIS ) gene to hepatocellular cancer .
30683895 2019
×
Entrez Id: 406906
Gene Symbol: MIR122
MIR122
Childhood Hepatocellular Carcinoma
0.040
Biomarker
BEFREE
miRNA122a regulation of gene therapy vectors targeting hepatocellular cancer stem cells.29805757 2018
×
Entrez Id: 406906
Gene Symbol: MIR122
MIR122
Childhood Hepatocellular Carcinoma
0.040
AlteredExpression
BEFREE
The role of miR-122 in the dysregulation of glucose-6-phosphate dehydrogenase (G6PD) expression in hepatocellular cancer .
29904144 2018
×
Entrez Id: 6528
Gene Symbol: SLC5A5
SLC5A5
Childhood Hepatocellular Carcinoma
0.040
Biomarker
BEFREE
Hypoxia-targeted 131I therapy of hepatocellular cancer after systemic mesenchymal stem cell-mediated sodium iodide symporter gene delivery.
27458162 2016
×
Entrez Id: 406906
Gene Symbol: MIR122
MIR122
Childhood Hepatocellular Carcinoma
0.040
Biomarker
BEFREE
Our findings suggest that enhanced glycolysis is associated with CD133 (+) stem-like characteristics and that metabolic reprogramming through miR-122 or PDK4 may represent a novel therapeutic approach for the treatment of hepatocellular cancer .
26506419 2015
×
Entrez Id: 406906
Gene Symbol: MIR122
MIR122
Childhood Hepatocellular Carcinoma
0.040
AlteredExpression
BEFREE
Reciprocal regulation of microRNA-122 and c-Myc in hepatocellular cancer : role of E2F1 and transcription factor dimerization partner 2.
24038073 2014
×
Entrez Id: 6528
Gene Symbol: SLC5A5
SLC5A5
Childhood Hepatocellular Carcinoma
0.040
Biomarker
BEFREE
Sodium iodide symporter (NIS )-mediated radiovirotherapy of hepatocellular cancer using a conditionally replicating adenovirus.23038026 2013
×
Entrez Id: 6528
Gene Symbol: SLC5A5
SLC5A5
Childhood Hepatocellular Carcinoma
0.040
Biomarker
BEFREE
Image-guided, tumor stroma-targeted 131I therapy of hepatocellular cancer after systemic mesenchymal stem cell-mediated NIS gene delivery.
21587211 2011
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
Childhood Hepatocellular Carcinoma
0.030
GeneticVariation
BEFREE
Majority of AFB1 associated hepatocellular cancer cases carry TP53 mutant DNA, which is an indicator of AFB1 exposure, as well as hepatocellular cancer risk.
30594067 2019
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Childhood Hepatocellular Carcinoma
0.030
Biomarker
BEFREE
Preoperative Serum IL6, IL8, and TNF -<i>α</i> May Predict the Recurrence of Hepatocellular Cancer .
31781194 2019
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
Childhood Hepatocellular Carcinoma
0.030
Biomarker
BEFREE
Here we found that suppressing TIP60 inhibited p53 K120 acetylation and thus rescued apoptosis induced by glucose deprivation in hepatocellular cancer cells.
29174981 2018
×
Entrez Id: 3939
Gene Symbol: LDHA
LDHA
Childhood Hepatocellular Carcinoma
0.030
Biomarker
BEFREE
The miR-383-LDHA axis regulates cell proliferation, invasion and glycolysis in hepatocellular cancer .
28293396 2017
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Childhood Hepatocellular Carcinoma
0.030
Biomarker
BEFREE
Adenovirus encoding XAF-1 and TNF‑α in the same open reading frame efficiently inhibits hepatocellular cancer cells.
27121136 2016
×
Entrez Id: 3939
Gene Symbol: LDHA
LDHA
Childhood Hepatocellular Carcinoma
0.030
Biomarker
BEFREE
Lactate dehydrogenase A (LDHA ), which is a key enzyme in the glycolysis signaling pathway, was found to be a target of miR‑34a in hepatocellular cancer cells.26956717 2016
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Childhood Hepatocellular Carcinoma
0.030
GeneticVariation
BEFREE
Our meta-analyses suggest that TNF -<i>α</i> T-857C polymorphism may be associated with increased risk of gastric cancer and hepatocellular cancer development.
28115787 2016