Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0281899
Disease: Prolapsed lumbar disc
Prolapsed lumbar disc 		0.030 AlteredExpression BEFREE Osthole exerts analgesic effect on radicular inflammatory pain in LDH rat model, by down-regulating the mRNA expression of the target gene of COX-2 via inhibiting ERK activation in the spinal dorsal horn. 28486232

2017
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0281899
Disease: Prolapsed lumbar disc
Prolapsed lumbar disc 		0.030 AlteredExpression BEFREE Moreover, higher expression of IL-21, IL-17, and COX-2 was found in the protein and mRNA levels in disc tissues from LDH patients than in normal disc tissues. 26742440

2015
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0281899
Disease: Prolapsed lumbar disc
Prolapsed lumbar disc 		0.030 Biomarker BEFREE However, the role of cyclooxygenase-2 in lumbar disc herniation has never been addressed. 12435978

2002