Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
CUI: C0340044
Disease: Acute exacerbation of chronic obstructive airways disease
Acute exacerbation of chronic obstructive airways disease 		0.040 Biomarker BEFREE In addition, LQZS could inhibit the production of proinflammatory cytokines in BALF, including IL-6 and IL-17A and downregulate the secretion of NE and MCP-1, indicating that LQZS could limit inflammatory responses in AECOPD. 30800170

2019
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
CUI: C0340044
Disease: Acute exacerbation of chronic obstructive airways disease
Acute exacerbation of chronic obstructive airways disease 		0.040 Biomarker BEFREE The expressions and significance of APN, D-D, IL-17 and hs-CRP in patients with acute exacerbation of chronic obstructive pulmonary disease. 30338815

2018
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
CUI: C0340044
Disease: Acute exacerbation of chronic obstructive airways disease
Acute exacerbation of chronic obstructive airways disease 		0.040 Biomarker BEFREE Intriguingly, the ratios of Th1/Th2 and IL-17/IgE were lower in AECOPD patients compared with the other two groups. 29950127

2018
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
CUI: C0340044
Disease: Acute exacerbation of chronic obstructive airways disease
Acute exacerbation of chronic obstructive airways disease 		0.040 AlteredExpression BEFREE We found that serum IL-1β and IL-17 levels in acute exacerbation of COPD subjects were significantly higher than that in stable COPD or control subjects and were positively correlated to serum C-reactive protein levels, neutrophil % and smoking status (pack-years) but negatively correlated with FEV<sub>1</sub>% predicted in COPD patients. 28490868

2017