Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3558
Gene Symbol: IL2
IL2
CUI: C0345904
Disease: Malignant neoplasm of liver
Malignant neoplasm of liver 		0.350 Biomarker BEFREE Our study elucidates that IL-2/S-15/Akti expanded Tils and represent a viable source for the cellular therapy for patients with hepatocellular cancer. 31827396

2019
Entrez Id: 3558
Gene Symbol: IL2
IL2
CUI: C0345904
Disease: Malignant neoplasm of liver
Malignant neoplasm of liver 		0.350 Biomarker BEFREE Thereby, the aim of this study is to verify whether cytokine IL-2 could increase the anti-cancer effects of sorafenib on liver cancer in vitro. 30476722

2019
Entrez Id: 3558
Gene Symbol: IL2
IL2
CUI: C0345904
Disease: Malignant neoplasm of liver
Malignant neoplasm of liver 		0.350 Biomarker BEFREE IL-2 augments the sorafenib-induced apoptosis in liver cancer by promoting mitochondrial fission and activating the JNK/TAZ pathway. 30459526

2018
Entrez Id: 3558
Gene Symbol: IL2
IL2
CUI: C0345904
Disease: Malignant neoplasm of liver
Malignant neoplasm of liver 		0.350 Biomarker BEFREE In particular, besides some cytokines like IFN-α and IL-2, several Toll-like receptor (TLR) agonists like BCG, MPL, and imiquimod are also licensed to be used in patients with several malignancies nowadays, and the first artificial small noncoding RNA (microRNA) mimic, MXR34, has entered phase I clinical study against liver cancer, implying their potential application in cancer therapy. 27240457

2016
Entrez Id: 3558
Gene Symbol: IL2
IL2
CUI: C0345904
Disease: Malignant neoplasm of liver
Malignant neoplasm of liver 		0.350 Biomarker BEFREE Transfection of IL-2 and/or IL-12 genes into spleen in treatment of rat liver cancer. 15259063

2004