Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1522
Gene Symbol: CTSZ
CTSZ
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.040 Biomarker BEFREE A panel of 11 prostate-derived proteins including IGKV3D-20, RNASET2, TACC2, ANXA7, LMOD1, PRCP, GYG1, NDUFV1, H1FX, APOBEC3C, and CTSZ display the potential to stratify patients from low and high PCa grade groups. 31576646

2019

Entrez Id: 1522
Gene Symbol: CTSZ
CTSZ
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.040 AlteredExpression BEFREE Here we present profilin 1, a known tumor suppressor, as a target for cathepsin X carboxypeptidase activity in prostate cancer PC-3 cells. 23326535

2013

Entrez Id: 1522
Gene Symbol: CTSZ
CTSZ
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.040 Biomarker BEFREE IGF-I receptor phosphorylation is impaired in cathepsin X-deficient prostate cancer cells. 23152410

2012

Entrez Id: 1522
Gene Symbol: CTSZ
CTSZ
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.040 Biomarker BEFREE The high expression levels of cathepsin X both in PIN and invasive adenocarcinomas of the prostate suggest that cathepsin X may play a role in the early tumorigenesis of prostate cancer. 15162377

2004