Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0524909
Disease: Hepatitis B, Chronic
Hepatitis B, Chronic
0.100 GeneticVariation BEFREE A meta-analysis of the correlation between the HLA-DRB1*03 allele and chronic hepatitis B in the Han Chinese population. 25325831

2015

Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0524909
Disease: Hepatitis B, Chronic
Hepatitis B, Chronic
0.100 GeneticVariation BEFREE Association of human leukocyte antigen DQB1 and DRB1 alleles with chronic hepatitis B. 25009391

2014

Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0524909
Disease: Hepatitis B, Chronic
Hepatitis B, Chronic
0.100 GeneticVariation BEFREE Relationship of HLA-DRB1 alleles with hepatocellular carcinoma development in chronic hepatitis B patients. 22499074

2012

Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0524909
Disease: Hepatitis B, Chronic
Hepatitis B, Chronic
0.100 Biomarker BEFREE Frequencies of HLA-DRB1*12 in the cirrhosis and liver cancer groups were significantly higher than those in the chronic hepatitis B (CHB) patients. 22367481

2012

Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0524909
Disease: Hepatitis B, Chronic
Hepatitis B, Chronic
0.100 GeneticVariation BEFREE HLA-DRB1*010101 allele is closely associated with poor virological response to lamivudine therapy in patients with chronic hepatitis B. 22156484

2011

Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0524909
Disease: Hepatitis B, Chronic
Hepatitis B, Chronic
0.100 GeneticVariation BEFREE Association of HLA-DRB1*13 and TNF-alpha gene polymorphisms with clearance of chronic hepatitis B infection and risk of hepatocellular carcinoma in Thai population. 18070287

2007

Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0524909
Disease: Hepatitis B, Chronic
Hepatitis B, Chronic
0.100 GeneticVariation BEFREE High positivities of HLA-DRB1 *07 allele and HBV genotype C are closely associated with the lower response to interferon-alpha therapy for chronic hepatitis B. 16094724

2005

Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0524909
Disease: Hepatitis B, Chronic
Hepatitis B, Chronic
0.100 Biomarker BEFREE Low-resolution DNA typing kit was used to determine HLA-DR-1 and -DQB1 genes in 72 patients with chronic hepatitis B (CHB) and HLA-DRB1 in 200 healthy people ready to donate their bone marrow in Shanghai. 16237774

2005

Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0524909
Disease: Hepatitis B, Chronic
Hepatitis B, Chronic
0.100 GeneticVariation BEFREE Curative effects of interferon-alpha and HLA-DRB1 -DQA1 and -DQB1 alleles in chronic viral hepatitis B. 15237447

2004

Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0524909
Disease: Hepatitis B, Chronic
Hepatitis B, Chronic
0.100 Biomarker BEFREE HLA-DRB1*0301, HLA-DQA1*0501 and HLA-DQB1*0301 are closely related with susceptibility to chronic hepatitis B, and HLA-DRB1*1101/1104 and HLA-DQA1*0301 are closely related with resistance to chronic hepatitis B. 14562382

2003

Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0524909
Disease: Hepatitis B, Chronic
Hepatitis B, Chronic
0.100 GeneticVariation BEFREE For example, some investigators reported the association of the HLA class II alleles such as DRB1*1302 or HLA-DR13 or DQA1*0501-DQB1*0301-DQB1*1102 haplotypes with acute and/or chronic hepatitis B virus infection, respectively. 12679901

2003

Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0524909
Disease: Hepatitis B, Chronic
Hepatitis B, Chronic
0.100 GeneticVariation BEFREE The HLA class II molecule DR12 and its allele DRB1*1201 are associated with protection against chronic hepatitis B in Zhejiang Province, China. 14599975

2003

Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0524909
Disease: Hepatitis B, Chronic
Hepatitis B, Chronic
0.100 GeneticVariation BEFREE In the first study the class II allele HLA-DRB1*1301-02 was found in 4 of 70 subjects with chronic hepatitis B virus infection (5.7%) compared to 27 of 101 healthy controls (26.7%, relative risk 0.17; p=0.001; p(corr)=0.025). 9075656

1997