Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5052
Gene Symbol: PRDX1
PRDX1
CUI: C0546837
Disease: Malignant neoplasm of esophagus
Malignant neoplasm of esophagus
0.340 AlteredExpression BEFREE We found that an antioxidant protein peroxiredoxin I (Prx I) was upregulated in human EC tissues as well as in EC cell lines. 27650197

2017

Entrez Id: 5052
Gene Symbol: PRDX1
PRDX1
CUI: C0546837
Disease: Malignant neoplasm of esophagus
Malignant neoplasm of esophagus
0.340 GeneticVariation BEFREE Our data suggested that polymorphisms of Prdx 1, 2 and 6 were not associated with esophageal cancer. 22215146

2012

Entrez Id: 5052
Gene Symbol: PRDX1
PRDX1
CUI: C0546837
Disease: Malignant neoplasm of esophagus
Malignant neoplasm of esophagus
0.340 Biomarker BEFREE Silencing Prx1 and/or Prx5 sensitizes human esophageal cancer cells to ionizing radiation and increases apoptosis via intracellular ROS accumulation. 21468086

2011

Entrez Id: 5052
Gene Symbol: PRDX1
PRDX1
CUI: C0546837
Disease: Malignant neoplasm of esophagus
Malignant neoplasm of esophagus
0.340 AlteredExpression BEFREE Except p21, Prdx1 (reported by us) and IGFBP3, the behaviour/expression of 12 highly responsive genes has still not been reported in esophageal cancer cells. 17671705

2007