Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma 		0.560 Biomarker BEFREE Association of Notch-1, osteopontin and stem-like cells in ENU-glioma malignant process. 30140373

2018
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma 		0.560 Biomarker BEFREE The literature review suggests that OPN may play important roles in the development and progression of selected cancers of children and young adults, including acute lymphoblastic leukemia, malignant gliomas, AT/RT and Langerhans cell histiocytosis. 28326824

2017
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma 		0.560 AlteredExpression BEFREE Our findings show re-activation of the embryonic-type transcriptional regulation of SPP1 in malignant gliomas and point to the importance of SPP1-CD44 interactions in self-renewal and pluripotency glioma initiating cells. 28030801

2017
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma 		0.560 AlteredExpression BEFREE Osteopontin and splice variant expression level in human malignant glioma: radiobiologic effects and prognosis after radiotherapy. 23891093

2013
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma 		0.560 AlteredExpression BEFREE Five potential markers (CD44 antigen (CD44), growth arrest and DNA-damage-inducible, alpha (GADD45A), fibronectin 1 (FN1), CD63 antigen (CD63) and secreted phosphoprotein 1 (SPP1)) showed expression patterns that correlated significantly with malignant glioma. 20150644

2010
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma 		0.560 Biomarker BEFREE Elucidation of regulatory mechanisms for OPN induction in glioma cells should facilitate rational design of novel therapeutics for human malignant gliomas. 9615723

1998