Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 442890
Gene Symbol: MIR133B
MIR133B
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
0.100 Biomarker BEFREE The endogenous expression level of miR-133b is sufficient for inducing cisplatin resistance, which suggests that miR-133b may be a biomarker for cisplatin resistance in osteosarcoma. 29399170

2018

Entrez Id: 442890
Gene Symbol: MIR133B
MIR133B
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
0.100 AlteredExpression BEFREE miR-133b was significantly down-regulated while FGFR1 robustly up-regulated in OS tissues and OS cell lines, when compared to normal bone tissues and normal osteoblasts, respectively. 30574019

2018

Entrez Id: 442890
Gene Symbol: MIR133B
MIR133B
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
0.100 Biomarker BEFREE Our results, although obtained in a small series of cases, confirming the high molecular homology with human OS suggesting a potential role of miR-1 and miR-133b as biomarkers for canine OS treatment. 29272721

2018

Entrez Id: 442890
Gene Symbol: MIR133B
MIR133B
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
0.100 Biomarker BEFREE Taken together, these findings will shed light on the role and mechanism of miR-133b in regulating osteosarcoma cell growth via the miR-133b/Sirt1 axis, and miR-133b may serve as a potential therapeutic target in osteosarcoma in the future. 28059051

2017

Entrez Id: 442890
Gene Symbol: MIR133B
MIR133B
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
0.100 Biomarker BEFREE In conclusion, the present study demonstrated that FOXC1, targeted by miR-133b, may promote cell proliferation and migration in OS. 28912845

2017

Entrez Id: 442890
Gene Symbol: MIR133B
MIR133B
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
0.100 AlteredExpression BEFREE In this study, we aimed to explore the effects of PCA on osteosarcoma MG63 cells by regulation of miR-133b, as well as its underlying mechanisms. 28251881

2017

Entrez Id: 442890
Gene Symbol: MIR133B
MIR133B
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
0.100 Biomarker BEFREE BACKGROUND MicroRNA-133b (miR-133b) has been reported to be involved in many diseases, including ovarian cancer and osteosarcoma. 27802259

2016

Entrez Id: 442890
Gene Symbol: MIR133B
MIR133B
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
0.100 AlteredExpression BEFREE Collectively, the aberrant expression of miR-133b and miR-206 may be implicated in tumorigenesis and tumor progression of osteosarcoma. 25120799

2014

Entrez Id: 442890
Gene Symbol: MIR133B
MIR133B
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
0.100 AlteredExpression BEFREE Our data assessed specific miRNA profiling deregulation in OS clinical samples and suggest that the expression of miR-1 and miR-133b may control cell proliferation and cell cycle through MET protein expression modulation. 23229283

2013

Entrez Id: 442890
Gene Symbol: MIR133B
MIR133B
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone
0.100 Biomarker BEFREE This study provides a new insight into miRNAs dysregulation in osteosarcoma, and indicates that miR-133b may play as a tumor suppressor gene in osteosarcoma. 24391788

2013