Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 8821
Gene Symbol: INPP4B
INPP4B
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.040 Biomarker BEFREE These findings reveal that INPP4B(high) has an unexpected role consistent with oncogenesis in AML, in contrast to its previously reported tumor-suppressive role in epithelial cancers. 25736236

2015
Entrez Id: 8821
Gene Symbol: INPP4B
INPP4B
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.040 Biomarker BEFREE Instead, the qualitative regulation of PI3K-AKT2 signaling by INPP4B provides a mechanism for their cooperation in suppressing thyroid tumorigenesis and metastasis. 25883022

2015
Entrez Id: 8821
Gene Symbol: INPP4B
INPP4B
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.040 Biomarker BEFREE Activation of SGK3 downstream of PIK3CA and INPP4B is required for 3D proliferation, invasive migration, and tumorigenesis in vivo. 25458846

2014
Entrez Id: 8821
Gene Symbol: INPP4B
INPP4B
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.040 AlteredExpression BEFREE The findings indicate that epigenetic inactivation of INPP4B is one of the key mechanisms in activating PI3K/AKT signaling cascade and playing a role in the tumorigenesis of NPC. 25126743

2014