Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2903
Gene Symbol: GRIN2A
GRIN2A
CUI: C0598608
Disease: Hyperhomocysteinemia
Hyperhomocysteinemia 		0.210 Biomarker BEFREE Using pharmacological inhibitors targeting the NMDAR subtypes, the study further demonstrates that inhibition of GluN2A-containing NMDARs significantly reduces ischemic brain damage in hyperhomocysteinemic rats but not in control rats, indicating that hyperhomocysteinemia-mediated exacerbation of ischemic brain injury involves GluN2A-NMDAR signaling. 30885791

2019