Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5604
Gene Symbol: MAP2K1
MAP2K1
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.130 Biomarker BEFREE MAPK kinase 1 (MEK1) is the upstream protein kinase of ERK that can activate ERK/MAPK signaling pathway. microRNA 203 (MiR-203) down-regulation is found to be associated with prostate cancer pathogenesis. 29949147

2018
Entrez Id: 5604
Gene Symbol: MAP2K1
MAP2K1
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.130 Biomarker BEFREE Here we show that PI3K-C2β regulates mitogen-activated protein kinase kinase (MEK1/2) and extracellular signal-regulated kinase (ERK1/2) activation in prostate cancer (PCa) cells. 26983806

2016
Entrez Id: 5604
Gene Symbol: MAP2K1
MAP2K1
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.130 AlteredExpression BEFREE Our results demonstrated that both transient and stable ectopic Id-1 expression in prostate cancer LNCaP cells led to activation of the Raf/MEK1/2 signaling pathway. 12466969

2002