Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5175
Gene Symbol: PECAM1
PECAM1
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
0.040 GeneticVariation BEFREE In 42 cases of high CD31 score, five-year survival rate (87%) of patients with lung cancer showing mature tumor vessels was significantly better than that (69%) of patients with immature tumor vessels. 29970531

2018

Entrez Id: 5175
Gene Symbol: PECAM1
PECAM1
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
0.040 Biomarker BEFREE In clinical specimens of lung cancer, the number of fibrocyte-like cells is significantly increased in bevacizumab-treated tumours, and correlates with the number of treatment cycles, as well as CD31-positive vessels. 26635184

2015

Entrez Id: 5175
Gene Symbol: PECAM1
PECAM1
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
0.040 Biomarker BEFREE When tested in a mouse model for lung cancer, repeated treatment with DACC/siRNA(CD31) reduced formation of lung metastases and increased life span in a mouse model of experimental lung metastasis. 24390281

2014

Entrez Id: 5175
Gene Symbol: PECAM1
PECAM1
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
0.040 Biomarker BEFREE CD31 and HIF1a were also found to be elevated in lung cancer. 23275310

2013