Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 10257
Gene Symbol: ABCC4
ABCC4
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma 		0.030 Biomarker BEFREE Our findings demonstrate a role for ABCC4 in neuroblastoma cell proliferation and chemoresistance and provide rationale for a strategy where inhibition of ABCC4 should both attenuate the growth of neuroblastoma and sensitise tumours to ABCC4 chemotherapeutic substrates. 28735070

2017
Entrez Id: 10257
Gene Symbol: ABCC4
ABCC4
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma 		0.030 Biomarker BEFREE Endogenous substrates of ABCC1 and ABCC4 that may be potential candidates affecting neuroblastoma biology include molecules such as prostaglandins and leukotrienes. 25640269

2015
Entrez Id: 10257
Gene Symbol: ABCC4
ABCC4
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma 		0.030 Biomarker BEFREE These results suggest that MRP4 will be a useful prognostic marker for neuroblastoma and that clinical trials of irinotecan as a neuroblastoma treatment should monitor MRP4 expression. 15827327

2005