DisGeNET - a database of gene-disease associations

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Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	471
Gene Symbol:	ATIC

ATIC

CUI:	C0751606
Disease:	Adult Acute Lymphocytic Leukemia

Adult Acute Lymphocytic Leukemia

0.010

PosttranslationalModification

BEFREE

We also show for the first time that AICAr in combination with MTX significantly induces Akt phosphorylation in ALL.

2011