DisGeNET - a database of gene-disease associations

Source: BEFREE

Disease: Adult Acute Lymphocytic Leukemia ×

Gene: ABCC3 ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	8714
Gene Symbol:	ABCC3

ABCC3

CUI:	C0751606
Disease:	Adult Acute Lymphocytic Leukemia

Adult Acute Lymphocytic Leukemia

0.030

AlteredExpression

BEFREE

No relationship was found between of MVP/LRP, MRP3 and ABCG2 genes expression and ALL prognoses.

24145140

2014

Entrez Id:	8714
Gene Symbol:	ABCC3

ABCC3

CUI:	C0751606
Disease:	Adult Acute Lymphocytic Leukemia

Adult Acute Lymphocytic Leukemia

0.030

GeneticVariation

BEFREE

In conclusion, MRP3 A-189 T polymorphism was associated with treatment responses in ALL, likely due to the change in MRP3 efflux.

21606946

2012

Entrez Id:	8714
Gene Symbol:	ABCC3

ABCC3

CUI:	C0751606
Disease:	Adult Acute Lymphocytic Leukemia

Adult Acute Lymphocytic Leukemia

0.030

Biomarker

BEFREE

Our results suggest that MRP3 is involved in drug resistance in childhood ALL.

12816874

2003