Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0856825
Disease: Acute GVH disease
Acute GVH disease 		0.050 GeneticVariation BEFREE However, no significant association was detected between the IL1B polymorphism in recipients and the development of aGVHD. 23659674

2013
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0856825
Disease: Acute GVH disease
Acute GVH disease 		0.050 Biomarker BEFREE The Nlrp3 inflammasome components Nlrp3 and Asc, which are required for pro-IL-1β cleavage, were critical for the full manifestation of GvHD. 23980097

2013
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0856825
Disease: Acute GVH disease
Acute GVH disease 		0.050 Biomarker BEFREE Single nucleotide polymorphisms (SNPs) of the interleukin 1 (IL-1) family have been implicated in acute graft-versus-host disease and mortality postallogeneic hematopoietic stem cell transplantation (HSCT) in adults. 22395218

2012
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0856825
Disease: Acute GVH disease
Acute GVH disease 		0.050 GeneticVariation BEFREE Donor genotype for IL-1 receptor antagonist (IL-1Ra) has been associated with reduced aGvHD severity. 15566351

2004
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0856825
Disease: Acute GVH disease
Acute GVH disease 		0.050 GeneticVariation BEFREE We found no association between the occurrence of acute GVHD and donor and/or recipient polymorphisms of any of the three IL-1 genes. 12752101

2003