Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0856825
Disease: Acute GVH disease
Acute GVH disease
0.020 AlteredExpression BEFREE Low levels of IL-8 (p=0.04) on day +7 and IFN-γ (p=0.03) after engraftment were associated with grade II-IV acute GVHD. 28898706

2017

Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0856825
Disease: Acute GVH disease
Acute GVH disease
0.020 AlteredExpression BEFREE Acute graft-versus-host disease (GVHD) is a primary T-cell-mediated complication of allogeneic hematopoietic stem cell transplantation (HSCT), occurring when donor-derived T cells are stimulated by host antigen-presenting cells (APCs), enhanced by proinflammatory cytokines such as interleukin (IL)-1, IL-6, IL-8, and tumor necrosis factor (TNF)-alpha. 15449032

2004