Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 50616
Gene Symbol: IL22
IL22
CUI: C0856825
Disease: Acute GVH disease
Acute GVH disease 		0.060 Biomarker BEFREE Furthermore, short-term use of exogenous IL-22 posttransplant accelerates recovery of thymus without increasing severity of acute GVHD. 30557822

2019
Entrez Id: 50616
Gene Symbol: IL22
IL22
CUI: C0856825
Disease: Acute GVH disease
Acute GVH disease 		0.060 Biomarker BEFREE The tissue healing capacities of ILC via IL-22 in the context of allo-HSCT and GVHD has previously been demonstrated in a mouse model for acute GVHD. 31751473

2019
Entrez Id: 50616
Gene Symbol: IL22
IL22
CUI: C0856825
Disease: Acute GVH disease
Acute GVH disease 		0.060 Biomarker BEFREE IL-22 and IFN-I reduce the severity of acute GVHD after allo-HSCT with myeloablative TBI. 30503785

2019
Entrez Id: 50616
Gene Symbol: IL22
IL22
CUI: C0856825
Disease: Acute GVH disease
Acute GVH disease 		0.060 AlteredExpression BEFREE Levels of IL-22 increased in aGVHD mice. 30114627

2018
Entrez Id: 50616
Gene Symbol: IL22
IL22
CUI: C0856825
Disease: Acute GVH disease
Acute GVH disease 		0.060 Biomarker BEFREE To investigate the association between IL-22 and aGVHD, an anti-mouse IL-22 antibody (IL-22Ab) was used to ablate IL-22 activity in a mouse aGVHD model. 30159338

2018
Entrez Id: 50616
Gene Symbol: IL22
IL22
CUI: C0856825
Disease: Acute GVH disease
Acute GVH disease 		0.060 Biomarker BEFREE Thus, interfering with both IL-22 and type I IFN signaling may provide a novel approach to limit aGVHD. 26153763

2016