Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1581
Gene Symbol: CYP7A1
CYP7A1
CUI: C0947622
Disease: Cholecystolithiasis
Cholecystolithiasis 		0.030 GeneticVariation BEFREE The CYP7A1 -204A>C polymorphism is significantly associated with serum lipid levels in Asian population, but not gallbladder stone disease. 25103562

2014
Entrez Id: 1581
Gene Symbol: CYP7A1
CYP7A1
CUI: C0947622
Disease: Cholecystolithiasis
Cholecystolithiasis 		0.030 GeneticVariation BEFREE After subgroup stratifications on the basis of sex and gallstone status, CC genotype and variant allele of CYP7A1 -204 A>C imparted higher risk for GBC in women (P = .003, OR = 3.30, 95% CI = 1.5-7.2) and patients without gallstones (P = .045, OR = 1.91, 95% CI = 1.2-3.6). 20005541

2010
Entrez Id: 1581
Gene Symbol: CYP7A1
CYP7A1
CUI: C0947622
Disease: Cholecystolithiasis
Cholecystolithiasis 		0.030 GeneticVariation BEFREE The GBC pathogenesis by CYP7A1 polymorphism appears to be independent of gallstone pathway and probably involves genotoxicity due to lipid peroxidation mechanisms. 18178499

2008